Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063578 | 0.90 | CA1 (0.42) | TDP1LMNAMAPTGAAPDGFRB | |
| SCHEMBL3990255 | 0.86 | KDM4E (0.47) | TDP1MAPTGAAPDGFRBFGFR1 | |
| SCHEMBL14907284 | 0.84 | KDM4E (0.49) | TDP1LMNAMAPTGAACA1 | |
| SCHEMBL5918245 | 0.81 | HPGD (0.54) | MAPTCA1CA2ALDH1A1ELANE | |
| SCHEMBL15028056 | 0.80 | NR1H4 (0.53) | TDP1LMNAGAANR1H4ALDH1A1 | |
| SCHEMBL15701587 | 0.80 | NOTUM (0.48) | TDP1LMNAMAPTGAACA1 | |
| SCHEMBL17185501 | 0.79 | ALDH1A1 (0.40) | TDP1LMNAMAPTGAAPDGFRB | |
| SCHEMBL2427949 | 0.79 | HPGD (0.51) | TDP1LMNAMAPTALDH1A1P2RX3 | |
| SCHEMBL28370520 | 0.78 | KDM4E (0.44) | LMNAMAPTGAACA1CA2 | |
| SCHEMBL7711932 | 0.78 | CA12 (0.43) | LMNAMAPTCA1CA2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662211-A1 | G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) DEGRADATION COMPOUNDS AND USE THEREOF | Nanjing Huanbo Biotechnology Co., Ltd. (CN) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024165075-A1 | G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) DEGRADATION COMPOUNDS AND USE THEREOF | NANJING HUANBO BIOTECHNOLOGY CO., LTD. (CN) | 2024-08-15 | — | — | WO | disclosed |