Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | INSR | P06213 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1317687 | 1.00 | MAPT (0.60) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL31063860 | 0.85 | MAPT (0.47) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL31063683 | 0.81 | MAPT (0.64) | MAPTKDM4EALDH1A1TDP1INSR | |
| SCHEMBL14434817 | 0.79 | MAPT (0.61) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL4013003 | 0.78 | MAPT (0.60) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL18166876 | 0.77 | MAPT (0.57) | MAPTKDM4EALDH1A1TDP1INSR | |
| SCHEMBL18416406 | 0.75 | MAPT (0.54) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL4015595 | 0.75 | MAPT (1.00) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL31147096 | 0.74 | MAPT (0.55) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL1318387 | 0.74 | MAPT (0.55) | MAPTKDM4EALDH1A1TDP1INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4732907-A1 | STYRYL BENZOTHIAZOLIUM SALTS AND ITS USES AGAINST PARASITIC INFECTIONS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024200263-A1 | 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS α-SYNUCLEIN BINDING COMPOUNDS | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2024-10-03 | — | — | WO | disclosed |
| EP-4438597-A1 | 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS A-SYNUCLEIN BINDING COMPOUNDS | Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) | 2024-10-02 | — | — | EP | disclosed |