Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038663 | 0.98 | MAPT (0.57) | MAPTKDM4EALDH1A1TDP1GAA | |
| Iodide SCHEMBL31063683 | 0.81 | MAPT (0.64) | MAPTKDM4EALDH1A1TDP1GAA | |
| SCHEMBL14434817 | 0.79 | MAPT (0.61) | MAPTKDM4EALDH1A1TDP1GAA | |
| Iodide SCHEMBL31063757 | 0.78 | MAPT (0.60) | MAPTKDM4EALDH1A1TDP1GAA | |
| Iodide SCHEMBL4013272 | 0.77 | MAPT (0.57) | MAPTKDM4EALDH1A1TDP1GAA | |
| SCHEMBL8030094 | 0.75 | MAPT (0.54) | MAPTKDM4EALDH1A1TDP1GAA | |
| Iodide SCHEMBL4015595 | 0.75 | MAPT (1.00) | MAPTKDM4EALDH1A1TDP1GAA | |
| Iodide SCHEMBL1318387 | 0.74 | MAPT (0.55) | MAPTKDM4EALDH1A1TDP1GAA | |
| Iodide SCHEMBL31147096 | 0.74 | MAPT (0.55) | MAPTKDM4EALDH1A1TDP1GAA | |
| Bromide SCHEMBL3280970 | 0.74 | MAPT (0.53) | MAPTKDM4EALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4732907-A1 | STYRYL BENZOTHIAZOLIUM SALTS AND ITS USES AGAINST PARASITIC INFECTIONS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2026-04-29 | — | — | EP | disclosed |
| WO-2009085226-A2 | INHIBITORS OF CDC2-LIKE KINASES (CLKS) AND METHODS OF USE THEREOF | SIRTRIS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |