Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21643735 | 1.00 | NR4A2 (0.49) | NR4A2ALOX5P2RX7RHEBMTNR1A | |
| SCHEMBL6421659 | 0.82 | NR4A2 (0.49) | NR4A2P2RX7MTNR1AMTNR1BPIM1 | |
| SCHEMBL3953673 | 0.81 | MTNR1A (0.53) | NR4A2P2RX7MTNR1AMTNR1BPIM1 | |
| SCHEMBL13987128 | 0.81 | NR4A2 (0.47) | NR4A2ALOX5P2RX7MTNR1AMTNR1B | |
| SCHEMBL6421662 | 0.79 | NR4A2 (0.43) | NR4A2ALOX5P2RX7MTNR1AMTNR1B | |
| SCHEMBL15797610 | 0.78 | P2RX7 (0.50) | NR4A2ALOX5P2RX7PIM1PIM3 | |
| SCHEMBL15797560 | 0.77 | P2RX7 (0.54) | NR4A2P2RX7CREBBP | |
| SCHEMBL28730919 | 0.77 | NR4A2 (0.50) | NR4A2P2RX7PIM1PIM3CREBBP | |
| SCHEMBL9938223 | 0.75 | AXL (0.47) | NR4A2 | |
| SCHEMBL31347303 | 0.75 | AXL (0.47) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533581-B | PRC1 inhibitors and methods of treatment therewith | 密歇根大学董事会 | 2024-08-30 | — | — | CN | disclosed |