Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421662 | 0.90 | NR4A2 (0.43) | NR4A2CREBBPPIM3PIM1HTR3E | |
| SCHEMBL15797406 | 0.83 | NR4A2 (0.53) | NR4A2CREBBPPIM3PIM1MTNR1A | |
| SCHEMBL31065131 | 0.82 | NR4A2 (0.49) | NR4A2CREBBPPIM3PIM1MTNR1A | |
| SCHEMBL21643735 | 0.82 | NR4A2 (0.49) | NR4A2CREBBPPIM3PIM1MTNR1A | |
| SCHEMBL15822633 | 0.82 | P2RX7 (0.55) | NR4A2CREBBPPIM3PIM1MTNR1A | |
| SCHEMBL3953673 | 0.82 | MTNR1A (0.53) | NR4A2CREBBPPIM3PIM1HTR3E | |
| SCHEMBL15797560 | 0.82 | P2RX7 (0.54) | NR4A2CREBBPP2RX7 | |
| SCHEMBL912821 | 0.82 | NR4A2 (0.48) | NR4A2CREBBPPIM3PIM1MTNR1A | |
| SCHEMBL13987128 | 0.82 | NR4A2 (0.47) | NR4A2CREBBPPIM3PIM1HTR3E | |
| SCHEMBL31556367 | 0.82 | NR4A2 (0.48) | NR4A2CREBBPPIM3PIM1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500563-B | Cycloalkanopyrolocarbazole derivatives and the use thereof as PARP, VEGFR2 and MLK3 inhibitors | CEPHALON INC | 2015-05-06 | — | — | CN | disclosed |
| CN-101570505-B | Indole-2, 3-diformic ester compound and derivatives and synthetic method | JIAO NING | 2013-06-05 | — | — | CN | disclosed |
| CN-101570505-A | Indole-2, 3-diformic ester compound and derivatives and synthetic method | NING JIAO (CN) | 2009-11-04 | — | — | CN | disclosed |
| CN-100453546-C | Indolecarboxylic ester trimer and electrochemical cell using the same | IHARA CHEMICAL IND CO (JP) | 2009-01-21 | — | — | CN | disclosed |
| CN-1660853-A | Indolecarboxylic ester trimer and electrochemical cell using the same | IHARA CHEMICAL IND CO (JP) | 2005-08-31 | — | — | CN | disclosed |
| US-20050178659-A1 | Copolymer compound and electrochemical cell therewith | NEC TOKIN CORPORATION (JP) | 2005-08-18 | — | — | US | disclosed |