Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 7/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.49 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065358 | 0.87 | CCR5 (0.53) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL80676 | 0.87 | CCR5 (0.53) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL8166488 | 0.84 | CCR5 (0.58) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL23599912 | 0.82 | USP28 (0.54) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL7121592 | 0.82 | LRRK2 (0.49) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL6491785 | 0.82 | CCR5 (0.49) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL3915066 | 0.81 | CCR5 (0.60) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL7116275 | 0.81 | CCR5 (0.48) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL8161790 | 0.79 | CCR5 (0.59) | CCR5SLC6A4ALDH1A1USP28USP25 | |
| SCHEMBL17700565 | 0.78 | CCR5 (0.58) | CCR5SLC6A4ALDH1A1USP28USP25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602044-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | invIOs GmbH (AT) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |