SCHEMBL31065358

SCHEMBL31065358

FC(F)c1cc(Br)ccc1OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 6/20 0.53
SLC6A4 P31645 1/20 0.53
ALDH1A1 P00352 3/20 0.52
RAB9A P51151 1/20 0.52
USP28 Q96RU2 1/20 0.49
USP25 Q9UHP3 1/20 0.49
MAOB P27338 1/20 0.49
HTT P42858 2/20 0.48
LMNA P02545 2/20 0.46
USP2 O75604 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LRRK2 Q5S007 1/20 0.45
PTPN1 P18031 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80676 1.00 CCR5 (0.53) CCR5SLC6A4ALDH1A1RAB9AUSP28
SCHEMBL31065341 0.87 CCR5 (0.50) CCR5SLC6A4ALDH1A1RAB9AUSP28
SCHEMBL3915066 0.84 CCR5 (0.60) CCR5SLC6A4ALDH1A1RAB9AUSP28
SCHEMBL23599912 0.83 USP28 (0.54) CCR5SLC6A4ALDH1A1RAB9AUSP28
SCHEMBL8161790 0.83 CCR5 (0.59) CCR5SLC6A4ALDH1A1RAB9AUSP28
SCHEMBL18893982 0.83 SLC6A9 (0.46) SLC6A4ALDH1A1LMNALRRK2MAPT
SCHEMBL17700565 0.82 CCR5 (0.58) CCR5SLC6A4ALDH1A1RAB9AUSP28
SCHEMBL8166488 0.82 CCR5 (0.58) CCR5SLC6A4ALDH1A1RAB9AUSP28
SCHEMBL12337611 0.81 MAPT (0.49) CCR5ALDH1A1MAOBHTTLMNA
SCHEMBL11890513 0.81 CCR5 (0.56) CCR5SLC6A4ALDH1A1RAB9AUSP28

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602044-A1 SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF invIOs GmbH (AT) 2025-08-20 EP disclosed
WO-2024133605-A1 SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF INVIOS GMBH (AT) 2024-06-27 WO disclosed