Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD3 | Q8IV08 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065800 | 1.00 | PLD3 (0.32) | PLD3ITKUSP30GPR142TLR9 | |
| SCHEMBL31065783 | 0.90 | PLD3 (0.32) | PLD3ITKGPR142KDM4ESMN1; SMN2 | |
| SCHEMBL31065775 | 0.90 | PLD3 (0.32) | PLD3ITKGPR142KDM4ESMN1; SMN2 | |
| SCHEMBL31065780 | 0.90 | PLD3 (0.32) | PLD3ITKGPR142KDM4ESMN1; SMN2 | |
| SCHEMBL31065761 | 0.86 | PLD3 (0.35) | PLD3KDM4ESMN1; SMN2 | |
| SCHEMBL31065776 | 0.83 | GPR119 (0.32) | PLD3USP30 | |
| SCHEMBL30968034 | 0.75 | OPRM1 (0.32) | — | |
| SCHEMBL30968100 | 0.75 | PTAFR (0.35) | GPR142 | |
| SCHEMBL30968042 | 0.75 | PTAFR (0.35) | GPR142 | |
| SCHEMBL30968132 | 0.75 | PTAFR (0.35) | GPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |