Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159219 | 0.92 | HLCS (0.60) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL5817718 | 0.90 | HLCS (0.63) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL5821183 | 0.89 | HLCS (0.64) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL515856 | 0.89 | HLCS (0.64) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL2456107 | 0.89 | HLCS (0.64) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL30337427 | 0.89 | HLCS (0.58) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL5804916 | 0.88 | TDP1 (0.61) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL30800274 | 0.88 | TDP1 (0.61) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL13034043 | 0.85 | HLCS (0.59) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL15185874 | 0.85 | HLCS (0.67) | HLCSTDP1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510807-A | Polymer interactive molecule conjugates and methods of use thereof | 生命科技联合股份有限公司 | 2024-08-16 | — | — | CN | disclosed |