SCHEMBL31068046

SCHEMBL31068046

Cn1cc2c(Cl)c3nc(-c4cc(C(F)(F)F)nn4-c4ncccc4Cl)oc(=O)c3cc2n1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAT2A P31153 6/20 0.34
▸ KDM4E B2RXH2 2/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ RXRA P19793 2/20 0.30
▸ NR1H2 P55055 2/20 0.30
▸ NR1H3 Q13133 2/20 0.30
▸ CARM1 Q86X55 1/20 0.30
▸ PTGS2 P35354 2/20 0.30
▸ PTGS1 P23219 1/20 0.30
▸ FLT3 P36888 1/20 0.30
▸ SYK P43405 1/20 0.30
▸ AURKB Q96GD4 1/20 0.30
▸ DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30390038 0.93 MAT2A (0.35) MAT2AKDM4EL3MBTL1MEN1ALDH1A1
SCHEMBL25082877 0.93 MAT2A (0.35) MAT2AKDM4EL3MBTL1MEN1ALDH1A1
SCHEMBL2936337 0.87 PTGS2 (0.33) MAT2AKDM4EL3MBTL1MEN1ALDH1A1
SCHEMBL2936092 0.87 PTGS2 (0.32) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL30389696 0.86 KDM4E (0.34) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL2936258 0.86 KDM4E (0.34) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL2927349 0.86 RXRA (0.33) MAT2AKDM4EL3MBTL1MEN1ALDH1A1
SCHEMBL951016 0.85 PDPK1 (0.36) KDM4EL3MBTL1MEN1ALDH1A1MAPT
SCHEMBL2933919 0.85 PTGS2 (0.31) KDM4EL3MBTL1PTGS2PTGS1
SCHEMBL2935131 0.84 KDM4E (0.32) KDM4EL3MBTL1MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-08-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR DDT, NOS1, SLC11A2 MAT2A 351/4885KDM4E 2663/4885L3MBTL1 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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