Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30284879 | 0.93 | IDO1 (0.50) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL1055293 | 0.89 | IDO1 (0.61) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| Bromide SCHEMBL27566990 | 0.87 | IDO1 (0.59) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL5042302 | 0.87 | IDO1 (0.59) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL30284782 | 0.79 | ADRA1A (0.81) | IDO1ADRA1ATAAR1HTR2AAOC3 | |
| SCHEMBL30284698 | 0.78 | IDO1 (0.46) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL30284722 | 0.78 | ADRA1A (0.63) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL30284741 | 0.78 | ADRA1A (0.54) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL9676713 | 0.77 | ALDH1A1 (0.51) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL7060410 | 0.74 | ADRA1A (0.68) | IDO1ADRA1ATAAR1HTR2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294460-A1 | DEUTERATED ANALOGS AND DERIVATIVES OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE AND USES THEREOF | TERRAN BIOSCIENCES INC. | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294460-A1 | DEUTERATED ANALOGS AND DERIVATIVES OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE AND USES THEREOF | DBH, PNMT, BRD4 | IDO1 1212/4885ADRA1A 469/4885TAAR1 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.