Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30861233 | 0.90 | IDO1 (0.56) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL11825653 | 0.90 | IDO1 (0.56) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL11474043 | 0.79 | APLNR (0.43) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL31068484 | 0.78 | IDO1 (0.50) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL16480388 | 0.76 | HSD17B10 (0.41) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL1237860 | 0.76 | APLNR (0.58) | IDO1ADRA1ATAAR1HTR2ACA12 | |
| SCHEMBL30284782 | 0.75 | ADRA1A (0.81) | IDO1ADRA1ATAAR1HTR2AAOC3 | |
| SCHEMBL11864537 | 0.75 | ABCB1 (0.54) | — | |
| SCHEMBL15935637 | 0.75 | PKM (0.42) | IDO1ADRA1ATAAR1HTR2AHSD17B10 | |
| SCHEMBL8747259 | 0.75 | SLC6A4 (0.47) | IDO1ADRA1ATAAR1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387952-A1 | DEUTERATED ANALOGS AND DERIVATIVES OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE AND USES THEREOF | Terran Biosciences Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023351-A1 | DEUTERATED ANALOGS AND DERIVATIVES OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE AND USES THEREOF | TERRAN BIOSCIENCES INC. (US) | 2023-02-23 | — | — | WO | disclosed |