Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069539 | 0.84 | CYP3A4 (0.36) | CYP1A2CYP17A1CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL435024 | 0.83 | ACHE (0.45) | HSD17B10HTR2AHTR2CHTR2BACHE | |
| SCHEMBL17191862 | 0.71 | ACHE (0.32) | ACHEPIK3CG | |
| SCHEMBL1500134 | 0.69 | SDCBP (0.42) | MEN1KMT2A | |
| SCHEMBL22151644 | 0.69 | SRD5A1 (0.39) | HTR2AHTR2BACHEMEN1KMT2A | |
| SCHEMBL21101461 | 0.69 | ALDH1A1 (0.42) | CYP1A2HSD17B10TDP1HTR2AHTR2C | |
| SCHEMBL21117718 | 0.69 | ALDH1A1 (0.42) | HTR2AHTR2CHTR2BALDH1A1CA12 | |
| SCHEMBL22151641 | 0.69 | HTR2C (0.43) | HTR2AHTR2CHTR2BHPGD | |
| SCHEMBL31409475 | 0.69 | CRBN (0.44) | CYP1A2CYP3A4HSD17B10ALDH1A1MEN1 | |
| SCHEMBL18793920 | 0.69 | MEN1 (0.41) | TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580225-A | PRMT5-MTA synergistic inhibitor and application thereof | 甘李药业股份有限公司 | 2024-09-03 | — | — | CN | disclosed |