Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21117718 | 0.80 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1NFKB1 | |
| SCHEMBL22151644 | 0.80 | SRD5A1 (0.39) | MEN1KMT2AGAADPP4 | |
| SCHEMBL1500134 | 0.80 | SDCBP (0.42) | ESR2ESR1MEN1KMT2APRMT5 | |
| SCHEMBL30336648 | 0.80 | SDCBP (0.42) | ESR2ESR1MEN1KMT2APRMT5 | |
| SCHEMBL17191862 | 0.79 | ACHE (0.32) | POLB | |
| SCHEMBL25317766 | 0.77 | CRBN (0.47) | CRBNMAOAMAOBPRKCIESR2 | |
| SCHEMBL31098598 | 0.77 | CRBN (0.47) | CRBNMAOAMAOBPRKCIESR2 | |
| SCHEMBL22151637 | 0.76 | CYP11B1 (0.49) | PRMT5WDR77 | |
| SCHEMBL31409552 | 0.76 | ADAM17 (0.46) | CRBNMAOAMAOBPRKCIESR2 | |
| SCHEMBL24735067 | 0.76 | HTR2A (0.36) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006553-A1 | METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2025-01-02 | — | — | WO | disclosed |