Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 1.00 |
| ▸ | TSHR | P16473 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 11/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.87 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.71 |
| ▸ | CASP1 | P29466 | 3/20 | 0.71 |
| ▸ | CASP7 | P55210 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | TP53 | P04637 | 5/20 | 0.65 |
| ▸ | USP2 | O75604 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.64 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069737 | 1.00 | MAPT (1.00) | MAPTTSHRNPC1RAB9AMEN1 | |
| SCHEMBL31069736 | 0.86 | MAPT (0.81) | MAPTTSHRNPC1RAB9AMEN1 | |
| SCHEMBL24189918 | 0.79 | MAPT (0.71) | MAPTTSHRNPC1RAB9AMEN1 | |
| SCHEMBL22672410 | 0.74 | KMT2A (1.00) | MAPTTSHRNPC1RAB9AMEN1 | |
| SCHEMBL4876579 | 0.68 | MAPT (0.52) | MAPTTSHRNPC1RAB9AMEN1 | |
| SCHEMBL13842554 | 0.68 | P2RX3 (0.63) | MAPTTSHRNPC1RAB9AMEN1 | |
| SCHEMBL28640002 | 0.67 | KDM4E (1.00) | MAPTTSHRNPC1RAB9AMEN1 | |
| SCHEMBL4046168 | 0.66 | LTA4H (0.69) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4457331 | 0.66 | ADORA2A (0.72) | ADORA2AADORA1 | |
| SCHEMBL30488034 | 0.66 | ADORA2A (0.72) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118593506-A | Application of compound a or derivative thereof in preparing medicine for preventing and treating liver fibrosis diseases | 河北师范大学 | 2024-09-06 | — | — | CN | claimed |
| CN-118593506-A | Application of compound a or derivative thereof in preparing medicine for preventing and treating liver fibrosis diseases | 河北师范大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-118593506-A | Application of compound a or derivative thereof in preparing medicine for preventing and treating liver fibrosis diseases | 河北师范大学 | 2024-09-06 | — | — | CN | disclosed |