Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.81 |
| ▸ | MEN1 | O00255 | 10/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.81 |
| ▸ | CASP1 | P29466 | 3/20 | 0.81 |
| ▸ | CASP7 | P55210 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 9/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | TP53 | P04637 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.62 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069737 | 0.86 | MAPT (1.00) | MAPTMEN1KMT2ANPSR1CASP1 | |
| SCHEMBL31069729 | 0.86 | MAPT (1.00) | MAPTMEN1KMT2ANPSR1CASP1 | |
| SCHEMBL22672410 | 0.73 | KMT2A (1.00) | MAPTMEN1KMT2ANPSR1CASP1 | |
| SCHEMBL6480001 | 0.69 | MAPT (0.49) | MAPTMEN1KMT2ANPSR1CASP1 | |
| SCHEMBL24189918 | 0.68 | MAPT (0.71) | MAPTMEN1KMT2ANPSR1CASP1 | |
| SCHEMBL18988688 | 0.68 | ALDH1A1 (0.67) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL28394744 | 0.67 | KMT2A (0.67) | MAPTMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL3366418 | 0.66 | ADORA2A (0.56) | MAPTMEN1KMT2ANPSR1CASP1 | |
| SCHEMBL28640002 | 0.66 | KDM4E (1.00) | MAPTMEN1KMT2ANPSR1CASP1 | |
| SCHEMBL13195727 | 0.66 | TLR7 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118593506-A | Application of compound a or derivative thereof in preparing medicine for preventing and treating liver fibrosis diseases | 河北师范大学 | 2024-09-06 | — | — | CN | disclosed |