Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070502 | 0.93 | HSD11B1 (0.45) | HSD11B1DHODHSLC6A4HTR1AHTR2A | |
| SCHEMBL31083719 | 0.91 | HSD11B1 (0.47) | HSD11B1DHODHSLC6A4HTR1AACHE | |
| SCHEMBL31070447 | 0.90 | PRKAB2 (0.38) | DHODHICMTMTNR1AMTNR1BHSD17B3 | |
| SCHEMBL31070603 | 0.90 | HSD17B3 (0.47) | ICMTHTR2AHTR2CHTR2BMTNR1A | |
| SCHEMBL31070471 | 0.89 | MAPT (0.46) | HSD11B1ICMTSLC6A4HTR1AHTR2C | |
| SCHEMBL31070544 | 0.89 | ICMT (0.43) | HSD11B1ICMTSLC6A4HTR1AHTR2A | |
| SCHEMBL31070609 | 0.87 | PRKAB2 (0.42) | ICMTSLC6A4HTR1AHTR2CHTR2B | |
| SCHEMBL31070557 | 0.84 | TRPV1 (0.42) | HSD11B1ICMTHTR2AHTR2CHTR2B | |
| SCHEMBL31083763 | 0.84 | HSD11B1 (0.48) | HSD11B1SLC6A4HTR1AHTR2AACHE | |
| SCHEMBL31070522 | 0.83 | HSD11B1 (0.42) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |