Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070471 | 0.93 | MAPT (0.46) | HSD11B1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL31083744 | 0.91 | PDE4D (0.45) | HSD11B1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL31070623 | 0.90 | ECE1 (0.40) | LMNACDK4CCND1KDM4EBRD4 | |
| SCHEMBL31070531 | 0.88 | MAP2 (0.44) | LMNAKIF11 | |
| SCHEMBL31070502 | 0.88 | HSD11B1 (0.45) | HSD11B1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31070602 | 0.88 | FLT4 (0.42) | MAPTMEN1KMT2AUSP2LMNA | |
| SCHEMBL31070454 | 0.87 | PRKAB2 (0.43) | HSD11B1LMNA | |
| SCHEMBL31070637 | 0.86 | IMPDH2 (0.38) | TP53CDK4CCND1KDM4EBRD4 | |
| SCHEMBL31070512 | 0.86 | CCR2 (0.41) | MMP2MMP9KDM4EBRD4ALDH1A1 | |
| SCHEMBL31070509 | 0.84 | KIF11 (0.36) | MAPTLMNAPDE1CKDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |