Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070557 | 0.90 | TRPV1 (0.42) | TRPV1JAK2PRKD3MARK3PRKCI | |
| SCHEMBL31070513 | 0.89 | KIF11 (0.41) | KIF11IDO1NR4A2MAP2 | |
| SCHEMBL31070531 | 0.89 | MAP2 (0.44) | KIF11IDO1NR4A2MAP2 | |
| SCHEMBL31070518 | 0.86 | KIF11 (0.43) | KIF11IDO1NR4A2MAP2 | |
| SCHEMBL31070603 | 0.83 | HSD17B3 (0.47) | KIF11IDO1NR4A2MAP2 | |
| SCHEMBL31083725 | 0.80 | KIF11 (0.43) | KIF11ABCB1MAP2 | |
| SCHEMBL31070502 | 0.80 | HSD11B1 (0.45) | DHODH | |
| SCHEMBL31070555 | 0.78 | KIF11 (0.47) | KIF11IDO1NR4A2 | |
| SCHEMBL31083748 | 0.78 | KIF11 (0.48) | KIF11IDO1MAP2 | |
| SCHEMBL31070544 | 0.77 | ICMT (0.43) | KCNH2IDO1MAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |