Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070603 | 0.93 | HSD17B3 (0.47) | MAP2HSD17B3GABRPGABRDGABRA1 | |
| SCHEMBL31070513 | 0.92 | KIF11 (0.41) | MAP2IDO1KIF11NR4A2 | |
| SCHEMBL31083725 | 0.91 | KIF11 (0.43) | MAP2HSD17B3GABRPGABRDGABRA1 | |
| SCHEMBL31070502 | 0.89 | HSD11B1 (0.45) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL31070518 | 0.89 | KIF11 (0.43) | MAP2HSD17B3IDO1KIF11NR4A2 | |
| SCHEMBL31070482 | 0.89 | TRPV1 (0.43) | MAP2IDO1KIF11NR4A2 | |
| SCHEMBL31070522 | 0.88 | HSD11B1 (0.42) | KIF11LMNA | |
| SCHEMBL31070565 | 0.87 | PRKAB2 (0.41) | MAP2HSD17B3IDO1HTR2AHTR2C | |
| SCHEMBL31070454 | 0.86 | PRKAB2 (0.43) | HSD17B3IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL31083768 | 0.84 | HSD17B3 (0.45) | HSD17B3GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |