Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744185 | 0.90 | NR1H2 (0.67) | ABHD6ESR2NR1H2USP30CRBN | |
| SCHEMBL23124526 | 0.90 | ESR2 (0.69) | ABHD6ESR2NR1H2USP30CRBN | |
| SCHEMBL30593270 | 0.90 | ESR2 (0.69) | ABHD6ESR2NR1H2USP30CRBN | |
| SCHEMBL22638739 | 0.88 | ESR2 (0.52) | ABHD6ESR2HDAC1NR1H2CRBN | |
| SCHEMBL22638749 | 0.86 | ROCK2 (0.52) | ABHD6ESR2HDAC1NR1H2USP30 | |
| SCHEMBL31070640 | 0.86 | ESR2 (0.51) | ABHD6ESR2HDAC1NR1H2CRBN | |
| SCHEMBL20294405 | 0.86 | ABHD6 (0.49) | ABHD6ESR2HDAC1NR1H2USP30 | |
| SCHEMBL31070668 | 0.86 | TMEM97 (0.52) | ABHD6ESR2HDAC1NR1H2CRBN | |
| SCHEMBL31070625 | 0.85 | GPR119 (0.53) | ABHD6ESR2HDAC1NR1H2ROCK2 | |
| SCHEMBL28204780 | 0.85 | HDAC1 (0.47) | ABHD6ESR2HDAC1NR1H2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |