Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA7 | P43166 | 2/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19808618 | 0.75 | CA12 (0.50) | CA12CA2CA7CA14CA9 | |
| SCHEMBL19798451 | 0.75 | CA12 (0.46) | CA12CA2CA7CA14CA9 | |
| SCHEMBL10486723 | 0.70 | CA12 (0.46) | CA12CA2CA7CA14CA9 | |
| SCHEMBL17226609 | 0.70 | GRIN2D (0.48) | CA12CA2CA7CA14CA9 | |
| SCHEMBL60897 | 0.70 | GRIN2D (0.48) | EPHX2KMT2AMEN1GRIN2DGRIN3B | |
| SCHEMBL9651043 | 0.68 | CA1 (1.00) | CA12CA2CA7CA14CA9 | |
| SCHEMBL3117688 | 0.68 | PSEN1 (0.54) | CA12CA2CA7CA14CA1 | |
| SCHEMBL5817637 | 0.66 | LMNA (0.46) | CA12CA2CA7CA14CA9 | |
| SCHEMBL12416793 | 0.66 | EPHX2 (0.48) | CA12CA2CA7CA14CA9 | |
| SCHEMBL19798452 | 0.66 | GRIN2D (0.43) | CA12CA2CA7CA14CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984326-B1 | ACYCLIC SULFAMIDE DERIVATIVES | FUND IMABIS INST MEDITTERANEO PARA EL AVAN E DE LA BIOTECNOLOGIA Y LA INVESTIG SANITARIA (ES) | 2017-05-03 | — | — | EP | disclosed |
| US-8188312-B2 | Acyclic sulfamide derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2012-05-29 | — | — | US | disclosed |
| US-20100179224-A2 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2010-07-15 | — | — | US | disclosed |
| US-20100048712-A2 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2010-02-25 | — | — | US | disclosed |
| US-20090221710-A1 | Acyclic Sulfamide Derivatives | FUNDACION IMABIS. INSTITUTO MEDITERRANEO PARA EL AVANCE DE LA BIOTECNOLOGIA Y LA INVESTIGACION SANITARIA (ES) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179224-A2 | Acyclic Sulfamide Derivatives | SULT2A1, STS, SUCNR1 | CA12 1267/4885CA2 1092/4885CA7 2233/4885 |
| US-20090221710-A1 | Acyclic Sulfamide Derivatives | STS, LIPE, FABP4 | CA12 3033/4885CA2 2198/4885CA7 2841/4885 |
| US-20100048712-A2 | Acyclic Sulfamide Derivatives | SULT2A1, STS, SUCNR1 | CA12 1267/4885CA2 1092/4885CA7 2233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.