Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30935917 | 0.84 | ALDH1A1 (0.57) | TP53HTTMRGPRX4FOLH1ALDH1A1 | |
| SCHEMBL9582484 | 0.84 | ALDH1A1 (0.57) | TP53HTTMRGPRX4FOLH1ALDH1A1 | |
| SCHEMBL7651795 | 0.81 | FOLH1 (0.48) | FOLH1CYP1A2MCL1SYK | |
| SCHEMBL7482565 | 0.78 | SRC (0.53) | HTTALDH1A1CYP1A2NPC1MEN1 | |
| SCHEMBL31072687 | 0.78 | RXRA (0.56) | MRGPRX4HPGDSMN1; SMN2 | |
| SCHEMBL5636124 | 0.77 | SGMS2 (0.50) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2112736 | 0.76 | KDM4E (0.58) | ALDH1A1CYP1A2MEN1KMT2APOLB | |
| SCHEMBL9431635 | 0.76 | PLAU (0.50) | HTTMAPTSMN1; SMN2 | |
| SCHEMBL7888930 | 0.74 | NPC1 (0.58) | HTTALDH1A1CYP1A2NPC1KMT2A | |
| SCHEMBL228713 | 0.73 | KDM4E (0.56) | TP53ALDH1A1CYP1A2NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440000-A | N-phenylamide quinoline compound as well as preparation method and application thereof | 宁波大学 | 2024-08-06 | — | — | CN | disclosed |