Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15684095 | 0.79 | NPC1 (0.46) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL10973763 | 0.75 | NPC1 (0.61) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL10972981 | 0.73 | NPC1 (0.51) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL3107484 | 0.72 | — | — | |
| SCHEMBL10974043 | 0.72 | NPC1 (0.46) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL3369940 | 0.72 | NPC1 (0.50) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL3109526 | 0.71 | NPC1 (0.46) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL10970812 | 0.70 | NPC1 (0.42) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL10407149 | 0.70 | NPC1 (0.45) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL3107486 | 0.68 | NPC1 (0.39) | NPC1CASP3RAB9ASENP8NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841132-B2 | Method for detecting compounds containing sulfenic acid using a 1,3-cyclohexanedione-based probe | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130288268-A1 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2013-10-31 | — | — | US | disclosed |
| US-8486642-B2 | Method of synthesizing 1,3-cyclohexadione derived reagents useful for detection or isolation of sulfenic acid-containing compounds | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2013-07-16 | — | — | US | disclosed |
| US-20100317027-A1 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | POOLE LESLIE B | 2010-12-16 | — | — | US | disclosed |
| US-7803630-B2 | Method for detecting target compounds containing sulfenic acids using new reagents | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2010-09-28 | — | — | US | disclosed |
| US-20080070261-A1 | SULFENIC ACID-REACTIVE COMPOUNDS | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2008-03-20 | — | — | US | disclosed |
| US-7294748-B2 | Sulfenic acid-reactive compounds and their methods of synthesis | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2007-11-13 | — | — | US | disclosed |
| WO-2006044364-A2 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060084173-A1 | Sulfenic acid-reactive compounds and their methods of synthesis and use in detection or isolation of sulfenic acid-containing compounds | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070261-A1 | SULFENIC ACID-REACTIVE COMPOUNDS | QSOX1, SQOR, PRDX1 | NPC1 4823/4885CASP3 2845/4885RAB9A 1596/4885 |
| US-20100317027-A1 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | QSOX1, SQOR, TST | NPC1 4846/4885CASP3 3009/4885RAB9A 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.