Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157644 | 0.92 | TDP1 (0.42) | TDP1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL15920999 | 0.85 | TDP1 (0.36) | TDP1MEN1KMT2AALDH1A1MMP8 | |
| SCHEMBL29903714 | 0.84 | TDP1 (0.39) | TDP1MEN1KMT2AALDH1A1MMP8 | |
| SCHEMBL5855659 | 0.82 | TDP1 (0.43) | TDP1MEN1KMT2AALDH1A1MMP8 | |
| SCHEMBL19465643 | 0.79 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL3080153 | 0.79 | TDP1 (0.48) | TDP1MEN1KMT2AALDH1A1MMP8 | |
| SCHEMBL27430163 | 0.78 | ENPEP (0.37) | TDP1ALDH1A1AAK1HTT | |
| SCHEMBL15920997 | 0.77 | TDP1 (0.38) | TDP1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL20473354 | 0.77 | ALDH1A1 (0.40) | TDP1MEN1KMT2AALDH1A1MMP8 | |
| SCHEMBL9627652 | 0.77 | TDP1 (0.43) | TDP1MEN1KMT2AALDH1A1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024177984-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |