Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3478112 | 0.90 | TSHR (0.59) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8671212 | 0.90 | TSHR (0.59) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL7047802 | 0.85 | ALDH1A1 (0.48) | TSHRTDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9556010 | 0.84 | TDP1 (0.57) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4964088 | 0.84 | TDP1 (0.57) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL1355836 | 0.83 | TSHR (0.51) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29561089 | 0.83 | TSHR (0.51) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10169776 | 0.82 | KMT2A (0.40) | TSHRTDP1ALDH1A1MAPK1MAPT | |
| SCHEMBL12702875 | 0.82 | KMT2A (0.40) | TSHRTDP1ALDH1A1MAPK1MAPT | |
| SCHEMBL8703261 | 0.82 | CFD (0.49) | TSHRTDP1ALDH1A1PKMHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372867-B2 | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-12 | — | — | US | disclosed |
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CORPSCIENCE AG (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-2181100-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | Bayer CropScience AG (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2008122375-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | CYP4X1, AADAC, CYP3A7 | TSHR 953/4885TDP1 4169/4885ALDH1A1 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.