Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | PPIG | Q13427 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26115378 | 0.89 | LMNA (0.49) | LMNACYP1A2CYP3A4MAOAPPIB | |
| SCHEMBL22838048 | 0.85 | LMNA (0.51) | LMNACYP1A2CYP3A4MAOAPPIB | |
| SCHEMBL31078901 | 0.84 | LMNA (0.45) | LMNACYP1A2CYP3A4MAOAPPIB | |
| SCHEMBL10745657 | 0.84 | PIN1 (0.53) | CYP3A4MAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3860904 | 0.82 | ALDH1A1 (0.51) | LMNACYP1A2CYP3A4MAPTTSHR | |
| SCHEMBL18053924 | 0.81 | CYP1A2 (0.51) | LMNACYP1A2CYP3A4MAOAPPIB | |
| SCHEMBL940605 | 0.81 | LMNA (0.55) | LMNACYP1A2CYP3A4MAOAPPIB | |
| SCHEMBL10815802 | 0.81 | POLB (0.54) | LMNACYP1A2CYP3A4MAOAMAPT | |
| SCHEMBL665559 | 0.79 | CYP1A2 (0.53) | LMNACYP1A2CYP3A4MAOAPPIB | |
| SCHEMBL397134 | 0.79 | CYP1A2 (0.53) | LMNACYP1A2CYP3A4MAOAPPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651872-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155601-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-07-25 | — | — | WO | disclosed |