SCHEMBL397134

SCHEMBL397134

CCOC(=O)C(C)(C)c1ccc(N)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.53
CYP3A4 P08684 3/20 0.53
LMNA P02545 3/20 0.53
MAOA P21397 1/20 0.53
CNR2 P34972 7/20 0.51
RORC P51449 1/20 0.47
PPIB P23284 1/20 0.44
PPIA P62937 1/20 0.44
PPID Q08752 1/20 0.44
PPIG Q13427 1/20 0.44
NPC1 O15118 2/20 0.42
MAPT P10636 2/20 0.42
RAB9A P51151 2/20 0.42
MMP8 P22894 1/20 0.42
TSHR P16473 2/20 0.41
ABCB11 O95342 1/20 0.41
HTR2A P28223 1/20 0.41
PMP22 Q01453 1/20 0.41
PPARA Q07869 1/20 0.41
F2 P00734 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL12273902 0.98 CYP1A2 (0.51) CYP1A2CYP3A4LMNAMAOACNR2
SCHEMBL665559 0.86 CYP1A2 (0.53) CYP1A2CYP3A4LMNAMAOACNR2
Hydrochloric Acid SCHEMBL27869694 0.85 LMNA (0.46) CYP1A2CYP3A4LMNAMAOACNR2
SCHEMBL6279399 0.85 CNR2 (0.58) CYP1A2CYP3A4CNR2RORCNPC1
SCHEMBL18053924 0.84 CYP1A2 (0.51) CYP1A2CYP3A4LMNAMAOACNR2
SCHEMBL940605 0.84 LMNA (0.55) CYP1A2CYP3A4LMNAMAOAPPIB
SCHEMBL4115523 0.84 CNR2 (0.53) CYP3A4LMNACNR2RORCTSHR
SCHEMBL15630699 0.83 RORC (0.51) CYP1A2CYP3A4LMNACNR2RORC
SCHEMBL10169477 0.83 LMNA (0.49) CYP1A2CYP3A4LMNACNR2RORC
SCHEMBL27625366 0.83 PARP10 (0.50) CYP1A2CYP3A4LMNAMAOACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 518 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637430-B2 Interleukin-17 (IL-17) inhibitors HITGEN INC. (CN) 2026-05-26 US disclosed
EP-4177249-B1 IMMUNOMODULATOR HITGEN INC (CN) 2025-12-03 EP disclosed
US-20250340528-A1 TARGETED PROTEIN DEGRADATION MONTE ROSA THERAPEUTICS AG (CH) 2025-11-06 US disclosed
US-12459920-B2 Targeted protein degradation MONTE ROSA THERAPEUTICS AG (CH) 2025-11-04 US disclosed
US-20250243180-A1 TARGETED PROTEIN DEGRADATION MONTE ROSA THERAPEUTICS AG (CH) 2025-07-31 US disclosed
WO-2025024521-A1 SUBSTITUTED PIPERIDINEDIONES FOR TARGETED PROTEIN DEGRADATION MONTE ROSA THERAPEUTICS, INC. (US) 2025-01-30 WO disclosed
CN-113880766-B Immunomodulator 成都先导药物开发股份有限公司 2023-10-31 CN disclosed
CN-113880767-B Immunomodulator 成都先导药物开发股份有限公司 2023-10-13 CN disclosed
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed
US-20230227437-A1 IMMUNOMODULATOR HITGEN INC (CN) 2023-07-20 US disclosed
WO-1997021704-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO., INC. (US) 1997-06-19 WO disclosed
WO-1997021435-A1 ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE MERCK & CO., INC. (US) 1997-06-19 WO disclosed
US-4720506-A Immunomodulating agent NIPPON SHINYAKU COMPANY, LIMITED (JP) 1988-01-19 US disclosed
EP-0094599-B1 USE OF AMINOPHENYLACETIC ACID DERIVATIVES FOR THE MANUFACTURE OF AN IMMUNOMODULATING MEDICAL PREPARATION MITSUBISHI KASEI CORPORATION (JP) 1987-04-01 EP disclosed
EP-0052296-B1 GLUTAMINE DERIVATIVES USABLE FOR CURING IMMUNE DISEASES, METHODS FOR THEIR PREPARATION AND COMPOSITIONS COMPRISING SAID DERIVATIVES MITSUBISHI KASEI CORPORATION (JP) 1984-06-27 EP disclosed
US-4439448-A IMMUNOMODULATING ACTIVITY MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-03-27 US disclosed
EP-0094599-A1 Use of aminophenylacetic acid derivatives for the manufacture of an immunomodulating medical preparation MITSUBISHI KASEI CORPORATION (JP) 1983-11-23 EP disclosed
US-4348399-A Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives AMERICAN CYANAMID COMPANY (US) 1982-09-07 US disclosed
EP-0052296-A1 Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives MITSUBISHI KASEI CORPORATION (JP) 1982-05-26 EP disclosed
US-3997669-A ANTIINFLAMMATORY CIBA-GEIGY CORPORATION (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637430-B2 Interleukin-17 (IL-17) inhibitors IL17A, IL2, IL23R CYP1A2 161/4885CYP3A4 203/4885LMNA 4233/4885
US-20250243180-A1 TARGETED PROTEIN DEGRADATION NEK7, NEK1, RIPK1 CYP1A2 4493/4885CYP3A4 4744/4885LMNA 1266/4885
US-20230227437-A1 IMMUNOMODULATOR IL17A, IL2, IL2RA CYP1A2 274/4885CYP3A4 826/4885LMNA 4866/4885
US-12459920-B2 Targeted protein degradation NEK7, NEK1, RIPK1 CYP1A2 4503/4885CYP3A4 4744/4885LMNA 1246/4885
US-20250340528-A1 TARGETED PROTEIN DEGRADATION NEK7, NEK1, RIPK1 CYP1A2 4493/4885CYP3A4 4744/4885LMNA 1266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.