Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6347339 | 0.86 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL7564852 | 0.84 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL4773988 | 0.82 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL13387589 | 0.79 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL29892760 | 0.79 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL7564856 | 0.78 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL1699197 | 0.78 | SMN1; SMN2 (0.70) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL10192215 | 0.78 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL12411578 | 0.78 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL1690744 | 0.77 | FAAH (0.69) | RAB9ANPC1SMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651872-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155601-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-07-25 | — | — | WO | disclosed |