Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880801 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL31078910 | 0.81 | LMNA (0.45) | ALDH1A1POLBMAPTLMNAKDM4E | |
| SCHEMBL12736938 | 0.80 | POLB (0.50) | ALDH1A1POLBMAPTKMT2ALMNA | |
| SCHEMBL14102434 | 0.80 | POLB (0.50) | ALDH1A1POLBMAPTKMT2ALMNA | |
| SCHEMBL11841515 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL27370387 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL395369 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL664917 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL11039515 | 0.76 | ALDH1A1 (0.76) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL18053923 | 0.76 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651872-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155601-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-07-25 | — | — | WO | disclosed |