Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199136 | 0.85 | TSHR (0.49) | ALDH1A1POLBLMNAKDM4E | |
| SCHEMBL27370387 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL664917 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL395369 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL11841515 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL15271983 | 0.83 | GLO1 (0.48) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL31079281 | 0.82 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL18053923 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL11785712 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTPKMKMT2A | |
| SCHEMBL22838063 | 0.82 | ALDH1A1 (0.58) | ALDH1A1POLBMAPTPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| EP-3205645-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-10-23 | — | — | EP | disclosed |
| US-9957251-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-01 | — | — | US | disclosed |
| EP-3205645-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2017-08-16 | — | — | EP | disclosed |
| US-20170044132-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-02-16 | — | — | US | disclosed |
| US-8802886-B2 | Method for producing aromatic difluoroacetic acid ester | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-12 | — | — | US | disclosed |
| US-8802886-B2 | Method for producing aromatic difluoroacetic acid ester | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-12 | — | — | US | disclosed |
| US-8802886-B2 | Method for producing aromatic difluoroacetic acid ester | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-12 | — | — | US | disclosed |
| EP-2502898-A1 | PREPARATION METHOD FOR AROMATIC DIFLUOROACETIC ACID ESTER | Central Glass Company, Limited (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-20120220795-A1 | METHOD FOR PRODUCING AROMATIC DIFLUOROACETIC ACID ESTER | CENTRAL GLASS COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
| US-20120220795-A1 | METHOD FOR PRODUCING AROMATIC DIFLUOROACETIC ACID ESTER | CENTRAL GLASS COMPANY, LIMITED (JP) | 2012-08-30 | — | — | US | disclosed |
| EP-1768984-B1 | THIENOPYRIMIDINES USEFUL AS AURORA KINASE INHIBITORS | SUNESIS PHARMACEUTICALS INC (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20100179123-A1 | THIENOPYRIMIDINES USEFUL AS AURORA KINASE INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2010-07-15 | — | — | US | disclosed |
| US-7601725-B2 | Thienopyrimidines useful as Aurora kinase inhibitors | SUNESIS PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| EP-1768984-A1 | THIENOPYRIMIDINES USEFUL AS AURORA KINASE INHIBITORS | Sunesis Pharmaceuticals, Inc. (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006036266-A1 | THIENOPYRIMIDINES USEFUL AS AURORA KINASE INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2006-04-06 | — | — | WO | disclosed |
| US-20060035908-A1 | Thienopyrimidines useful as Aurora kinase inhibitors | SUNESIS PHARMACEUTICALS, INC. | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220795-A1 | METHOD FOR PRODUCING AROMATIC DIFLUOROACETIC ACID ESTER | DDC, AADAC, FNTB | ALDH1A1 84/4885POLB 1409/4885MAPT 3444/4885 |
| US-20100179123-A1 | THIENOPYRIMIDINES USEFUL AS AURORA KINASE INHIBITORS | AURKA, AURKB, AURKC | ALDH1A1 3035/4885POLB 1199/4885MAPT 1402/4885 |
| US-20060035908-A1 | Thienopyrimidines useful as Aurora kinase inhibitors | AURKA, AURKB, AURKC | ALDH1A1 2795/4885POLB 1108/4885MAPT 1512/4885 |
| US-20170044132-A1 | HETEROCYCLIC COMPOUND | CDK19, CDK9, CDK8 | ALDH1A1 3859/4885POLB 1011/4885MAPT 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.