Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29824791 | 0.87 | ZDHHC7 (0.34) | ZDHHC7ABCB1CA1CA2ALDH1A1 | |
| SCHEMBL31079658 | 0.83 | ZDHHC7 (0.38) | ZDHHC7ABCB1CA1CA2ALDH1A1 | |
| SCHEMBL16547562 | 0.82 | ZDHHC7 (0.37) | ZDHHC7ABCB1CA1CA2ALDH1A1 | |
| SCHEMBL11648130 | 0.73 | ZDHHC7 (0.48) | ZDHHC7ABCB1CA1CA2ALDH1A1 | |
| SCHEMBL11660609 | 0.72 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL5694365 | 0.71 | ZDHHC7 (0.52) | ZDHHC7ABCB1CA1CA2ALDH1A1 | |
| SCHEMBL6657457 | 0.70 | CA2 (0.43) | ZDHHC7CA1CA2ALDH1A1MAPT | |
| SCHEMBL29825333 | 0.70 | ZDHHC7 (0.38) | ZDHHC7ABCB1CA1CA2 | |
| SCHEMBL12851500 | 0.69 | ZDHHC7 (0.45) | ZDHHC7ABCB1CA1CA2MAPT | |
| SCHEMBL29056390 | 0.69 | CA2 (0.50) | ZDHHC7ABCB1CA1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | UNIV MICHIGAN REGENTS (US) | 2024-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240341301-A1 | ITACONATE AND DERIVATIVES THEREOF FOR THE PROTECTION OF CELLS, TISSUES, AND ORGANS | TNNI3, ALDH2, ALDH5A1 | ZDHHC7 811/4885ABCB1 3060/4885CA1 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.