Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491462 | 0.81 | SMN1; SMN2 (0.50) | LMNAALDH1A1MAPT | |
| SCHEMBL19181663 | 0.78 | CHEK1 (0.45) | CYP19A1LMNAMAPT | |
| SCHEMBL14798532 | 0.78 | SMN1; SMN2 (0.63) | LMNAALDH1A1MAPT | |
| SCHEMBL19182414 | 0.77 | CYP1A2 (0.47) | CYP19A1LMNAALDH1A1MAPTHPGD | |
| SCHEMBL4810294 | 0.77 | CRHBP (0.61) | LMNAALDH1A1FAAHMGLL | |
| SCHEMBL3649190 | 0.76 | CYP19A1 (0.46) | CYP19A1ALDH1A1MAPT | |
| SCHEMBL5260772 | 0.76 | MEN1 (0.46) | ALDH1A1MAPTHPGD | |
| SCHEMBL22634768 | 0.75 | CYP19A1 (0.43) | CYP19A1ALDH1A1MAPT | |
| SCHEMBL15248984 | 0.75 | ALDH1A1 (0.47) | CYP19A1ALDH1A1MAPT | |
| SCHEMBL9488146 | 0.75 | KAT2B (0.49) | CYP19A1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775277-A | Compounds as modulators of LRRK2, NUAK1 and/or TYK2 kinases for the treatment of, for example, autoimmune diseases | 原真股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-114793435-B | Compounds as modulators of LRRK2, NUAK1 and/or TYK2 kinases for the treatment of, for example, autoimmune diseases | 原真股份有限公司 | 2024-10-01 | — | — | CN | disclosed |