Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12480587 | 0.87 | MAOB (0.45) | MEN1KMT2AHPGDRAB9AHTT | |
| SCHEMBL8754543 | 0.85 | PYCR1 (0.50) | MEN1KMT2ARAB9AHTTALDH1A1 | |
| SCHEMBL4180366 | 0.80 | HTR2C (0.42) | MEN1KMT2ARAB9AHTTALDH1A1 | |
| SCHEMBL15051655 | 0.79 | HTR7 (0.47) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL4704482 | 0.78 | MEN1 (0.44) | MEN1KMT2AHPGDRAB9AHTT | |
| SCHEMBL18421556 | 0.77 | HPGD (0.45) | MEN1KMT2AHPGDRAB9AHTT | |
| SCHEMBL1893045 | 0.77 | PYCR1 (0.52) | MEN1KMT2AHPGDRAB9AHTT | |
| SCHEMBL31079746 | 0.76 | CYP19A1 (0.45) | HPGDALDH1A1MAPT | |
| SCHEMBL12481908 | 0.75 | TDP1 (0.43) | MEN1KMT2AHPGDRAB9AHTT | |
| SCHEMBL31411911 | 0.74 | NCEH1 (0.46) | MEN1KMT2AHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817297-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | Pfizer Products Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006056854-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2006-06-01 | — | — | WO | disclosed |