SCHEMBL3107995

SCHEMBL3107995

CCCC[C@](N)(CO)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ARG2 P78540 11/20 0.58
ARG1 P05089 10/20 0.58
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
THRB P10828 1/20 0.45
KMT2A Q03164 1/20 0.45
ODC1 P11926 1/20 0.44
FDPS P14324 3/20 0.42
SMPD1 P17405 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3108002 1.00 ARG2 (0.58) ARG2ARG1MEN1ALDH1A1CYP1A2
SCHEMBL185635 0.89 ARG1 (0.52) ARG2ARG1MEN1ALDH1A1CYP1A2
SCHEMBL3100239 0.86 ARG2 (0.52) ARG2ARG1MEN1ALDH1A1CYP1A2
SCHEMBL77047 0.86 ARG2 (0.52) ARG2ARG1MEN1ALDH1A1CYP1A2
Biphenyl SCHEMBL27607645 0.86 ARG1 (0.46) ARG2ARG1ALDH1A1KMT2A
Biphenyl SCHEMBL27607570 0.85 ARG1 (0.45) ARG2ARG1ALDH1A1KMT2A
SCHEMBL23010905 0.84 ARG1 (0.48) ARG2ARG1MEN1ALDH1A1CYP1A2
SCHEMBL6666220 0.84 ARG2 (0.63) ARG2ARG1MEN1ALDH1A1CYP1A2
SCHEMBL7465019 0.84 ARG2 (0.63) ARG2ARG1MEN1ALDH1A1CYP1A2
SCHEMBL14088071 0.84 ARG2 (0.53) ARG2ARG1MEN1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2239335-B1 PROCESS FOR PRODUCTION OF SERINE DERIVATIVE, AND PROTEIN FOR USE IN THE PROCESS AJINOMOTO KK (JP) 2013-02-27 EP disclosed
US-8372607-B2 Method for producing serine derivative and protein used for the same AJINOMOTO CO., INC. (JP) 2013-02-12 US disclosed
US-20100317068-A1 METHOD FOR PRODUCING SERINE DERIVATIVE AND PROTEIN USED FOR THE SAME AJINOMOTO CO., INC. (JP) 2010-12-16 US disclosed
EP-2239335-A1 PROCESS FOR PRODUCTION OF SERINE DERIVATIVE, AND PROTEIN FOR USE IN THE PROCESS Ajinomoto Co., Inc. (JP) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317068-A1 METHOD FOR PRODUCING SERINE DERIVATIVE AND PROTEIN USED FOR THE SAME SPR, AMD1, DAO ARG2 3627/4885ARG1 3039/4885MEN1 3040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.