Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 6/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 4/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070662 | 0.90 | IDO1 (0.38) | ECE1IDO1HTR6SIGMAR1UTS2R | |
| SCHEMBL30593227 | 0.89 | ECE1 (0.44) | ECE1HSD11B1ESR1ESR2KIF11 | |
| SCHEMBL31083752 | 0.89 | KIF11 (0.49) | ECE1HSD11B1IDO1KIF11HTR6 | |
| SCHEMBL30593317 | 0.89 | HSD11B1 (0.43) | HSD11B1ESR1ESR2 | |
| SCHEMBL31083748 | 0.89 | KIF11 (0.48) | ECE1HSD11B1ESR1ESR2IDO1 | |
| SCHEMBL30593296 | 0.87 | DRD2 (0.41) | HSD11B1KIF11HTR6 | |
| SCHEMBL29084839 | 0.87 | DRD2 (0.41) | HSD11B1KIF11HTR6 | |
| SCHEMBL29084783 | 0.86 | SLC6A4 (0.48) | ECE1IDO1 | |
| SCHEMBL30593237 | 0.86 | SLC6A4 (0.48) | ECE1IDO1 | |
| SCHEMBL30593229 | 0.86 | ESR1 (0.39) | ECE1HSD11B1ESR1ESR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742543-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |