Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362511 | 1.00 | TDP1 (0.60) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL311445 | 0.87 | ATM (0.55) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL13262511 | 0.84 | ATM (0.55) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL525939 | 0.83 | TDP1 (0.58) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL2891144 | 0.83 | TDP1 (0.58) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL30800770 | 0.83 | TDP1 (0.58) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL10757303 | 0.83 | ATM (0.58) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL1414035 | 0.83 | ATM (0.58) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL1349019 | 0.82 | TDP1 (0.53) | TDP1ATMALDH1A1MAPTMAPK1 | |
| SCHEMBL7737640 | 0.82 | TDP1 (0.53) | TDP1ATMALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820724-B2 | Method for preparing 2-ethyl-4-fluoro-1-nitrobenzene | ACCELA CHEMBIO CO., LTD. (CN) | 2023-11-21 | — | — | US | claimed |
| US-20220024850-A1 | METHOD FOR PREPARING 2-ETHYL-4-FLUORO-1-NITROBENZENE | ACCELA CHEMBIO CO., LTD. (CN) | 2022-01-27 | — | — | US | claimed |
| CN-110746307-B | Preparation method of 1-nitro-2-ethyl-4-fluorobenzene | 韶远科技（上海)有限公司 | 2021-07-06 | — | — | CN | claimed |
| WO-2021082752-A1 | PREPARATION METHOD FOR 1-NITRO-2-ETHYL-4-FLUOROBENZENE | 韶远科技（上海)有限公司 | 2021-05-06 | — | — | WO | claimed |
| CN-110746307-A | Preparation method of 1-nitro-2-ethyl-4-fluorobenzene | 韶远科技（上海)有限公司 | 2020-02-04 | — | — | CN | claimed |
| US-20250144094-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ERASCA, INC. | 2025-05-08 | — | — | US | disclosed |
| CN-114040911-B | As NAV1.8 2, 3-Dihydro-quinazoline Compounds as inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-10-22 | — | — | CN | disclosed |
| US-20240083896-A1 | Nitrogen Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-03-14 | — | — | US | disclosed |
| US-11820724-B2 | Method for preparing 2-ethyl-4-fluoro-1-nitrobenzene | ACCELA CHEMBIO CO., LTD. (CN) | 2023-11-21 | — | — | US | disclosed |
| US-11820724-B2 | Method for preparing 2-ethyl-4-fluoro-1-nitrobenzene | ACCELA CHEMBIO CO., LTD. (CN) | 2023-11-21 | — | — | US | disclosed |
| US-11820724-B2 | Method for preparing 2-ethyl-4-fluoro-1-nitrobenzene | ACCELA CHEMBIO CO., LTD. (CN) | 2023-11-21 | — | — | US | disclosed |
| WO-2023215494-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ERASCA, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |
| US-20080300242-A1 | Imidazopyridine Kinase Inhibitors | GLAXOSMITHKLINE LLC | 2008-12-04 | — | — | US | disclosed |
| US-20080300242-A1 | Imidazopyridine Kinase Inhibitors | GLAXOSMITHKLINE LLC | 2008-12-04 | — | — | US | disclosed |
| US-20080300242-A1 | Imidazopyridine Kinase Inhibitors | GLAXOSMITHKLINE LLC | 2008-12-04 | — | — | US | disclosed |
| US-4801717-A | PLANT GROWTH REGULATORS | ROUSSEL UCLAF (FR) | 1989-01-31 | — | — | US | disclosed |
| EP-0119892-B1 | HYDROXYL AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS GROWTH FACTORS FOR VEGETABLES AND COMPOSITIONS THEREOF | ROUSSEL-UCLAF (FR) | 1986-08-13 | — | — | EP | disclosed |
| EP-0119892-A1 | Hydroxyl amine derivatives, their preparation, their use as growth factors for vegetables and compositions thereof | ROUSSEL-UCLAF (FR) | 1984-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250144094-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ULK1, ULK2, ULK3 | TDP1 500/4885ATM 598/4885ALDH1A1 3129/4885 |
| US-20220024850-A1 | METHOD FOR PREPARING 2-ETHYL-4-FLUORO-1-NITROBENZENE | CYP2E1, NOS1, CBR1 | TDP1 1032/4885ATM 3068/4885ALDH1A1 165/4885 |
| US-20080300242-A1 | Imidazopyridine Kinase Inhibitors | ABL1, MAP3K19, MAP3K5 | TDP1 1064/4885ATM 724/4885ALDH1A1 3410/4885 |
| US-20240083896-A1 | Nitrogen Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors | SCN8A, SCN1A, SCN2A | TDP1 2847/4885ATM 3907/4885ALDH1A1 1362/4885 |
| US-11820724-B2 | Method for preparing 2-ethyl-4-fluoro-1-nitrobenzene | CYP2E1, NOS1, CBR1 | TDP1 1032/4885ATM 3068/4885ALDH1A1 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.