Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211477 | 0.89 | HPGD (0.46) | TP53MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3938216 | 0.88 | RHOA (0.46) | MAPK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3517759 | 0.82 | CCNT1 (0.49) | TSHRHPGDSRC | |
| SCHEMBL31469077 | 0.81 | SYK (0.41) | TP53TSHRMAPTSMN1; SMN2MEN1 | |
| SCHEMBL19624259 | 0.81 | NFKB1 (0.51) | LMNAMAPTSMN1; SMN2ABCG2ABCB1 | |
| SCHEMBL375687 | 0.78 | PDE4B (0.44) | MAPK1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL31083964 | 0.77 | LMNA (0.47) | MAPK1LMNATP53TSHRPDE5A | |
| SCHEMBL31572377 | 0.75 | PDE4B (0.44) | MAPTMEN1KMT2AALDH1A1PDE4B | |
| SCHEMBL2124418 | 0.74 | NFKB1 (0.57) | MAPK1LMNATP53TSHRPDE5A | |
| SCHEMBL19867173 | 0.74 | MAPT (0.54) | MAPK1LMNATP53TSHRPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674852-A1 | PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE | Innovstone Therapeutics Limited (CN) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024179493-A1 | PREPARATION METHOD FOR AND USE OF DIHYDROTHIENOPYRIMIDINE DERIVATIVE | 上海翊石医药科技有限公司 | 2024-09-06 | — | — | WO | disclosed |