Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 7/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | FRK | P42685 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | NEK4 | P51957 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624259 | 0.85 | NFKB1 (0.51) | EGFRCDK1CDK5MAPTRAB9A | |
| SCHEMBL375687 | 0.85 | PDE4B (0.44) | EGFRCSNK2A1MAPTRAB9AKMT2A | |
| SCHEMBL3938216 | 0.83 | RHOA (0.46) | EGFRCSNK2A1MAPTRAB9AMEN1 | |
| SCHEMBL13211477 | 0.82 | HPGD (0.46) | MAPTRAB9AALOX5MEN1KMT2A | |
| SCHEMBL31083985 | 0.81 | MAPK1 (0.49) | MAPTRAB9AMEN1KMT2ACYP3A4 | |
| SCHEMBL658170 | 0.76 | CYP3A4 (0.52) | SYKPIM1EGFRDYRK3PRKD3 | |
| SCHEMBL3517759 | 0.76 | CCNT1 (0.49) | CDK1CSNK2A1IRAK4TSHR | |
| SCHEMBL31469083 | 0.76 | PDE4B (0.47) | — | |
| SCHEMBL589243 | 0.75 | PLK4 (0.44) | EGFRCDK1SMN1; SMN2 | |
| SCHEMBL31491328 | 0.75 | KIF11 (0.41) | SYKMAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684313-A | Macrocyclic compound and preparation method and application thereof | 上海爱科百发生物医药技术股份有限公司 | 2025-03-25 | — | — | CN | disclosed |