Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205623 | 0.88 | MAPT (0.53) | MAPTDGKAADRA2AADRA1AALDH1A1 | |
| SCHEMBL11329144 | 0.88 | MAPT (0.53) | MAPTDGKAALDH1A1DNM1CYP3A4 | |
| SCHEMBL127983 | 0.85 | DGKA (0.47) | MAPTDGKAADRA2AADRA1AALDH1A1 | |
| SCHEMBL10511231 | 0.83 | MAPT (0.47) | MAPTDGKAADRA2AADRA1AALDH1A1 | |
| SCHEMBL30173728 | 0.83 | ADRA2A (0.43) | MAPTDGKAADRA2AADRA1AALDH1A1 | |
| SCHEMBL23159167 | 0.83 | MAPT (0.47) | MAPTDGKAADRA2AADRA1AALDH1A1 | |
| SCHEMBL20581506 | 0.83 | MAPT (0.47) | MAPTDGKAADRA2AADRA1AALDH1A1 | |
| SCHEMBL821822 | 0.83 | ADRA2A (0.43) | MAPTDGKAADRA2AADRA1AALDH1A1 | |
| SCHEMBL985537 | 0.83 | L3MBTL1 (0.52) | MAPTALDH1A1L3MBTL1HSD17B10TSHR | |
| SCHEMBL29175194 | 0.83 | L3MBTL1 (0.52) | MAPTALDH1A1L3MBTL1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143439-A | Bio-based flame retardant and application thereof in polylactic acid and/or polyhydroxyalkanoate | 中国科学院宁波材料技术与工程研究所 | 2023-12-01 | — | — | CN | claimed |
| CN-117143439-A | Bio-based flame retardant and application thereof in polylactic acid and/or polyhydroxyalkanoate | 中国科学院宁波材料技术与工程研究所 | 2023-12-01 | — | — | CN | disclosed |
| EP-2267133-B1 | METHOD FOR MAKING POLY(3-HYDROXYPROPRIONATE) | CJ RES CENTER LLC (US) | 2017-07-12 | — | — | EP | disclosed |
| US-8093022-B2 | polylactones produced in biological system selected from bacteria, yeasts, fungi and plants, expressing enzymes selected from polyhydroxyalkanoate synthase, acyl-CoA transferase and hydroxyacyl CoA transferase, and hydroxyacyl CoA synthetase | METABOLIX, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| EP-2267133-A2 | Method for making poly(3-hydroxyproprionate) | METABOLIX, INC. (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-1078068-B1 | POLYHYDROXYALKANOATE BIOPOLYMER COMPOSITIONS | METABOLIX INC (US) | 2010-09-29 | — | — | EP | disclosed |
| US-20080275208-A1 | POLYHYDROXYALKANOATE BIOPOLYMER COMPOSITIONS | METABOLIX, INC. DELAWARE | 2008-11-06 | — | — | US | disclosed |
| US-7202064-B2 | Polyhydroxyalkanoate biopolymer compositions | METABOLIX, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-20040033572-A1 | Polyhydroxyalkanoate biopolymer compositions | METABOLIX, INC. | 2004-02-19 | — | — | US | disclosed |
| US-6323010-B1 | PROVIDING SUBSTRATES WHICH COMPRISE 2-HYDROXYBUTYRIC ACID IN BIOLOGICAL SYSTEM WHICH IS GENETICALLY ENGINEERED TO EXPRESS ONE OR MORE ENZYMES SELECTED FROM THE GROUP CONSISTING OF POLYHYDROXYALKANOATE SYNTHASE, ACYL-COA TRANSFERASE, ETC. | METABOLIX, INC. | 2001-11-27 | — | — | US | disclosed |
| EP-1078068-A2 | POLYHYDROXYALKANOATE BIOPOLYMER COMPOSITIONS | METABOLIX, INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999061624-A2 | POLYHYDROXYALKANOATE BIOPOLYMER COMPOSITIONS | METABOLIX, INC. (US) | 1999-12-02 | — | — | WO | disclosed |