Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821930 | 0.88 | MGLL (0.45) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL2531971 | 0.85 | CA1 (0.43) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL23078940 | 0.85 | MAPT (0.46) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL17928371 | 0.85 | MAPT (0.50) | ADRA2AADRA1AMAPTALDH1A1MGLL | |
| SCHEMBL30173728 | 0.83 | ADRA2A (0.43) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL310867 | 0.83 | MAPT (0.47) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL1743791 | 0.82 | ADRA2A (0.42) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL22028559 | 0.80 | ADRA2A (0.54) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL1830290 | 0.80 | MGLL (0.38) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL10583483 | 0.80 | MAPT (0.44) | ADRA2AADRA1AMAPTBLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | ADRA2A 2333/4885ADRA1A 1186/4885MAPT 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.