Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117082 | 0.82 | NAMPT (0.41) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3115151 | 0.82 | BRD4 (0.37) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3112504 | 0.78 | REN (0.35) | CYP2C19CYP2C9OPRD1LMNAMAPT | |
| SCHEMBL3109368 | 0.78 | ALDH1A1 (0.43) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3109364 | 0.78 | ALDH1A1 (0.43) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL5244694 | 0.77 | HPGD (0.48) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3112309 | 0.75 | GAA (0.50) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3112318 | 0.75 | GAA (0.50) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL3114145 | 0.74 | CYP1A2 (0.42) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL5245617 | 0.74 | LMNA (0.54) | CYP1A2CYP2C19CYP2C9LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803822-B2 | Triazole derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20090105253-A1 | Triazole Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105253-A1 | Triazole Derivative and Use Thereof | F2R, HRH4, F2RL3 | HPGD 800/4885CYP1A2 418/4885CYP2C19 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.