Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244456 | 0.90 | LMNA (0.57) | LMNAALDH1A1MAPTHDAC1MIF | |
| SCHEMBL5246092 | 0.89 | EPHX2 (0.53) | MEN1KMT2ALMNACYP1A2CYP2C19 | |
| SCHEMBL5248174 | 0.89 | POLB (0.48) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5246361 | 0.89 | CCR1 (0.49) | LMNAMAPTHDAC1ROCK2 | |
| SCHEMBL5244366 | 0.89 | CCR1 (0.45) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL5246022 | 0.89 | CCR1 (0.43) | HPGDMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL5246999 | 0.89 | HDAC1 (0.46) | LMNAALDH1A1CYP1A2CYP2C19RECQL | |
| Trifluoroacetic Acid SCHEMBL5247370 | 0.88 | LMNA (0.48) | HPGDMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL5245992 | 0.88 | SMN1; SMN2 (0.52) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5249308 | 0.87 | RIPK1 (0.46) | HPGDMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |