Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091927 | 0.83 | PTGS1 (0.34) | TGFBR1KDM4EKDM4CHSD11B1MAPK14 | |
| SCHEMBL31091928 | 0.77 | KDM4E (0.33) | TGFBR1KDM4EKDM4CMAPK14PTGS2 | |
| SCHEMBL31091918 | 0.74 | KDM4E (0.42) | KDM4EKDM4CMAPK14KDM5BKDM5A | |
| SCHEMBL15331861 | 0.71 | SMN1; SMN2 (0.35) | SMN1; SMN2 | |
| SCHEMBL31091965 | 0.69 | MEN1 (0.36) | KDM4EHSD11B1MAPK14 | |
| SCHEMBL2561937 | 0.66 | — | — | |
| SCHEMBL1359122 | 0.65 | ALDH1A1 (0.50) | PTGS2SMN1; SMN2 | |
| SCHEMBL31387760 | 0.65 | ALDH1A1 (0.50) | PTGS2SMN1; SMN2 | |
| SCHEMBL2555076 | 0.65 | CYP1A2 (0.37) | HSD11B1MAPK14SMN1; SMN2 | |
| SCHEMBL29952633 | 0.65 | CYP1A2 (0.37) | HSD11B1MAPK14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220541-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |