Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091927 | 0.86 | PTGS1 (0.34) | MEN1KMT2AALDH1A1HSD11B1MAPK14 | |
| SCHEMBL20102296 | 0.74 | HCRTR1 (0.43) | KCNH2 | |
| SCHEMBL29117972 | 0.72 | TDP2 (0.41) | MEN1KMT2AKDM4E | |
| SCHEMBL31091868 | 0.69 | TGFBR1 (0.34) | HSD11B1MAPK14KDM4E | |
| SCHEMBL2687037 | 0.68 | SLC40A1 (0.39) | HTTIKBKB | |
| SCHEMBL29912312 | 0.68 | SLC40A1 (0.39) | HTTIKBKB | |
| SCHEMBL19868700 | 0.68 | NPC1 (0.31) | — | |
| SCHEMBL7930611 | 0.67 | PTGS2 (0.44) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19868912 | 0.67 | PARP1 (0.35) | IKBKB | |
| SCHEMBL21864476 | 0.67 | SMN1; SMN2 (0.35) | MEN1KMT2AALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220541-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |