Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091965 | 0.86 | MEN1 (0.36) | MAPK14MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL31091868 | 0.83 | TGFBR1 (0.34) | PTGS2MAPK14KDM4EKDM4CHSD11B1 | |
| SCHEMBL31091928 | 0.80 | KDM4E (0.33) | PTGS1PTGS2MAPK14KDM4EKDM4C | |
| SCHEMBL20102296 | 0.74 | HCRTR1 (0.43) | KCNH2KAT8CYP2C9CYP2C19 | |
| SCHEMBL29117972 | 0.72 | TDP2 (0.41) | TDP1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL31091918 | 0.71 | KDM4E (0.42) | MAPK14ALDH1A1KMT2AKDM4EKDM4C | |
| SCHEMBL29952633 | 0.70 | CYP1A2 (0.37) | MAPK14TDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL2555076 | 0.70 | CYP1A2 (0.37) | MAPK14TDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL15330833 | 0.70 | MAPT (0.38) | PTGS1PTGS2TDP1ALDH1A1KDM4E | |
| SCHEMBL21864476 | 0.70 | SMN1; SMN2 (0.35) | PTGS1PTGS2TDP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220541-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |