Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091927 | 0.80 | PTGS1 (0.34) | KDM4EKDM4CMAPK14TGFBR1PTGS1 | |
| SCHEMBL31091868 | 0.77 | TGFBR1 (0.34) | KDM4EKDM4CMAPK14TGFBR1KDM5A | |
| SCHEMBL31091918 | 0.74 | KDM4E (0.42) | KDM4EKDM4CMAPK14DPP4KDM4A | |
| SCHEMBL11258939 | 0.66 | PTGS2 (0.43) | KDM4EPTGS1PTGS2 | |
| SCHEMBL2552652 | 0.66 | CYP1A2 (0.35) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31091965 | 0.66 | MEN1 (0.36) | KDM4EMAPK14 | |
| SCHEMBL95723 | 0.66 | ERN1 (0.50) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL9712527 | 0.65 | ERN1 (0.42) | — | |
| SCHEMBL29824002 | 0.65 | ERN1 (0.42) | — | |
| SCHEMBL2559888 | 0.65 | SLC34A1 (0.40) | MAPK14PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220541-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |