Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | AKT2 | P31751 | 2/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091944 | 0.85 | AKT1 (0.43) | AKT1AKT2PADI4NPC1RAB9A | |
| SCHEMBL31298326 | 0.82 | ALDH1A1 (0.41) | AKT1AKT2PADI4NPC1RAB9A | |
| SCHEMBL31091962 | 0.81 | AKT1 (0.42) | AKT1AKT2PADI4NPC1RAB9A | |
| SCHEMBL31190886 | 0.81 | AKT1 (0.42) | AKT1AKT2PADI4NPC1RAB9A | |
| SCHEMBL30944806 | 0.80 | AKT1 (0.45) | AKT1AKT2NPC1RAB9AALDH1A1 | |
| SCHEMBL20937883 | 0.78 | KIF11 (0.46) | AKT1AKT2NPC1RAB9AALDH1A1 | |
| SCHEMBL30276230 | 0.78 | KIF11 (0.46) | AKT1AKT2NPC1RAB9AALDH1A1 | |
| SCHEMBL976070 | 0.77 | KDM4E (0.48) | AKT1AKT2RAB9AALDH1A1KDM4E | |
| SCHEMBL31190888 | 0.76 | AKT1 (0.42) | AKT1AKT2PADI4NPC1RAB9A | |
| SCHEMBL20923411 | 0.76 | PADI4 (0.59) | AKT1AKT2PADI4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220541-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |