Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276230 | 1.00 | KIF11 (0.46) | KIF11AKT1AKT2MAPTKDM4E | |
| SCHEMBL28399640 | 0.89 | AKT1 (0.38) | AKT1AKT2MAPTKDM4EALDH1A1 | |
| SCHEMBL20937885 | 0.82 | PADI4 (0.35) | AKT1AKT2MAPTKDM4EALDH1A1 | |
| SCHEMBL31091925 | 0.78 | AKT1 (0.46) | AKT1AKT2MAPTKDM4EALDH1A1 | |
| SCHEMBL20937699 | 0.77 | PTGER4 (0.46) | AKT1AKT2MAPTKDM4EALDH1A1 | |
| SCHEMBL20937231 | 0.73 | PTGER4 (0.48) | AKT1AKT2ADORA3 | |
| SCHEMBL30276188 | 0.73 | PTGER4 (0.48) | AKT1AKT2ADORA3 | |
| SCHEMBL31298326 | 0.73 | ALDH1A1 (0.41) | AKT1AKT2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL20920821 | 0.72 | AKT1 (0.49) | AKT1AKT2MAPTKDM4EALDH1A1 | |
| SCHEMBL976070 | 0.72 | KDM4E (0.48) | AKT1AKT2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697785-B1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| EP-3697785-B1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| US-11426412-B2 | Imidazo-pyridine compounds as PAD inhibitors | Jubilant Epipad LLC (US) | 2022-08-30 | — | — | US | disclosed |
| US-20200237771-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC | 2020-07-30 | — | — | US | disclosed |
| US-20200237771-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC | 2020-07-30 | — | — | US | disclosed |
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200237771-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | PADI4, PADI1, PADI2 | KIF11 3758/4885AKT1 1915/4885AKT2 2837/4885 |
| US-11426412-B2 | Imidazo-pyridine compounds as PAD inhibitors | PADI4, PADI1, PADI2 | KIF11 3758/4885AKT1 1915/4885AKT2 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.