Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471190 | 1.00 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1ALOX15 | |
| SCHEMBL28014589 | 0.89 | BRS3 (0.44) | RAB9ASMN1; SMN2NPC1KDM4EPOLB | |
| SCHEMBL11509759 | 0.88 | BCAT2 (0.35) | RAB9ASMN1; SMN2NPC1ALDH1A1ALOX15 | |
| SCHEMBL15412720 | 0.85 | ALDH1A1 (0.46) | RAB9ASMN1; SMN2NPC1ALDH1A1ALOX15 | |
| SCHEMBL10811664 | 0.85 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPTCYP2C9POLB | |
| SCHEMBL29395860 | 0.85 | BCAT2 (0.53) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL10664169 | 0.85 | KDM4C (0.47) | SMN1; SMN2NPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL11357674 | 0.85 | ALDH1A1 (0.39) | RAB9ASMN1; SMN2NPC1ALDH1A1ALOX15 | |
| SCHEMBL27274151 | 0.85 | BCAT2 (0.53) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL29628297 | 0.84 | TSHR (0.46) | RAB9ASMN1; SMN2ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |